Wednesday 11 February 2009

Regression analysis of mean quality-adjusted survival time based on pseudo-observations

Gisela Tunes da Silva and John Klein have a new paper in Statistics in Medicine. This applies the pseudo-observations approach to the estimation of mean quality adjusted survival time (QAS). They assume an identity link function for the relationship between mean QAS and covariates at baseline. This direct regression is analogous to similar approaches taken in the competing risks context by Graw, Gerds and Schumacher in Lifetime Data Analysis.

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